Genetic examinations list

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MARVELD2 gene testing (exon 4) – early non-syndromic AR deafness

Sequencing the coding region of exon 4 in the MARVELD2 gene, which is a common cause of hearing loss in the Roma ethnic group.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Isolated DNA from chorionic villi, Isolated DNA from amniotic fluid, Isolated DNA from cordocentesis, DNA isolated from the product of conception, DNA isolated from cultured cells

Turnover Time:

3 weeks

STATIM

1 week

HLA DQA1*05 (rs2097432) testing for anti-TNF biological therapy

Detection of rs2097432 (HLA DQA1*05 allele) by real-time PCR diagnostic kit.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood

Turnover Time:

3 weeks

STATIM

1 week

HLA DQA1*05 typing (immunogenicity)

Detection of the presence of HLA DQA1*05*01 and HLA DQA1*05*05 alleles by real-time PCR.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood

Turnover Time:

3 weeks

STATIM

1 week

Haemochromatosis – H63D, S65C, C282Y mutation in the HFE gene

HFE gene testing by real-time PCR is performed to detect the most common p.C282Y, p.H63D and p.S65C mutations associated with hereditary haemochromatosis.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Chorionic villi, Amniotic fluid, Cord blood, Conception product, Cultured cells, Isolated DNA from cordocentesis, Isolated DNA from chorionic villi, DNA isolated from the product of conception, Isolated DNA from amniotic fluid

Turnover Time:

3 weeks

STATIM

3 days